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DeCS
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Descriptor English:
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Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
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Descriptor Spanish:
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Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma
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Descriptor Portuguese:
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Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo
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Synonyms English:
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PGC 1 alpha Protein
PGC-1-alpha Protein
PPARGC 1 alpha Protein
PPARGC-1-alpha Protein
PPARGC1a Protein
Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 alpha
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Tree Number:
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D12.644.360.024.314.650
D12.776.157.057.080.650
D12.776.157.725.813.875
D12.776.476.024.394.650
D12.776.660.675.650
D12.776.664.962.813.875
D12.776.930.617.650
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Definition English:
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A transcriptional co-activator for NUCLEAR RECEPTORS. It is characterized by an N-terminal LxxLL sequence, a region that interacts with PPAR GAMMA, and a C-terminal RNA RECOGNITION MOTIF. It increases expression of MITOCHONDRIAL UNCOUPLING PROTEIN to regulate genes involved in metabolic reprogramming in response to dietary restriction and the integration of CIRCADIAN RHYTHMS with ENERGY METABOLISM. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56537
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Unique Identifier:
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D000071248
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Occurrence in VHL:
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Similar:
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DeCS
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